Nonclinical Biostatistics Working Group

Nonclinical Biostatistics Bayesian Preclinical/Discovery Scientific Working Group

About this workstream

Co-chairs: Tony Pourmohamad and Yushi Liu

The Bayesian workstream was established in 2019 with the aim of advancing the use and acceptance of Bayesian methods within the nonclinical statistics space. The workstream, which falls under the umbrella of the ASA Biopharmaceutical Nonclinical Working Group (NCBWG), includes several industry and academia members who form small sub-teams to work on specific projects aimed promoting Bayesian methods.

How to get involved

If you are interested in staying up-to-date in our work or possibly jumping into a certain project, we would like to add you to our email list (please contact one of the co-chairs to be added to the list). There is no obligation to participate. As new projects are identified, we will reach out to the broad group and seek volunteers to fill specific roles in the projects. Therefore, you can choose to simply stay informed or become active in a particular initiative. Either way, our hope is to build a broader community of interest / contributors that will help to advance the use of Bayesian methods.

Current Projects

Project

Contributors

Write a manuscript on A survey of Bayesian statistical methods in biomarker discovery  and early clinical development (Submitted)

Erina Paul (Merck)

Avid M. Afzal (AZ)

Roland Brown (Biogen)

Shanshan Cao (Lilly)

Yushi Liu (Lilly)

Tatiana Matejovicova (DeepMind)

Anupreet Porwal (Univ of Wash)

Zhe Sun (Lilly)

Richard Baumgartner (Merck)

Himel Mallick (Merck)

Manuscript on Bayesian tutorial by company

(i)               Merck (submitted)

(ii)              Lilly (in progress)

(iii)            AZ (in progress)

Erina Paul (Merck)

Arinjita Bhattacharyya (Merck)

Richard Baumgartner (Merck)

Himel Mallick (Merck)

Ixavier Alonzo Higgins (Lilly)

Jiyuan Fang (Lilly)

Zhe Sun (Lilly)

Avid Afzal (AZ)

Past Projects

Year

Project

Access

2023

A survey of Bayesian statistical methods in biomarker discovery and early clinical development

2023

NCB 2023 Bayesian Workshop

Diya Luwis (JNJ)

Will Landau (Lilly)

2021

2021 Nonclinical Biostatistics Conference – Invitation of Dr. Jason Roy for Bayesian Regression Trees short course