NCB-2025-Presentations

NCB 2025 Presentations

Click on the presentation title to open the presentation slides. 

Oral Presentations

Area(s)

Title

Presenter

CMC

Optimal Experimental Designs for Process Robustness Studies

Peter Goos (KU Leuven)

 CMC

Enhancing Patient-Centered Care: Bridging Pharma and Medical Device Technologies Through Collaborative Statistical Practices

Yiming Peng (Genentech), Yenny Webb Vargas (Genentech)

CMC

To Dilute or Not to Dilute: Nominal Titer Dosing for Genetic Medicines

Tianhui Zhang (Lilly)

CMC

Shelf-Life Estimation and Internal Release Limits accounting for a Series of Storage Excursions through Bayesian Kinetic Hierarchical Model

Ji Young Kim (Takeda)

CMC

Measurement System Analysis: Practical Considerations for Setting Acceptance Criteria in Gage R&R Studies

Hao Wang (BMS)

CMC

Statistical assessment for analytical comparability between pre-change and post-change processes

Bill Pikounis (J&J)

CMC

Leveraging an Experimental Database to Inform an OMARS designed experiment

Peili Wang (Pfizer)

CMC

Bayesian Approach to address common data challenges in CMC

Faith Dunbar (Takeda)

Student Presentation

Tolerance Interval Construction via Hierarchical Dirichlet Processes

Seokjun Choi (University of California, Santa Cruz)

Student Presentation

Testing the Equivalence of Intra-Subject Covariance Matrices in Crossover Designs

Bo Liu (University of Maryland, Baltimore County)

Student Presentation

Differential Projection Pursuit: A machine learning method to find regions with maximal difference between distributions

Mahan Dastgiri (Rutgers University)

Discovery

Statistical Inference for Heterogeneous Treatment Effects Discovered by Generic Machine Learning in Randomized Experiments

Dr. Michael Lingzhi Li (Harvard Business School)

 Discovery

Translating Lupus: Comparative Transcriptional Profiles of Preclinical Lupus Models and Their Relevance to Human Disease

Ching-Yun (Veavi) Chang (Lilly)

 

Discovery

Large Row-Constrained Supersaturated Designs for High-throughput Screening

Byran Smucker (Henry Ford Health)

Discovery

Insights about experiment design and data analysis in non-clinical studies learnt from Lord’s Paradox

Weiliang Qiu (Sanofi)

Discovery

The A-R-Cs of Supporting High-Throughput Screening Assays

Traymon Beavers (J&J)

Discovery

Do hemolyzed samples interfere with cytokines quantification?

Thi Dong Binh Tran (Pfizer)

Discovery

Navigating the Uncertain Waters of Black-Box QSAR Modeling with Conformal Prediction Intervals

Gregory Steeno (Pfizer)

Discovery

Foundation Models for Robust Object Tracking in Home-Cage Behavioral Phenotyping Studies

Reuben Retnam (Takeda)

Safety

Challenges in Early-stage Prediction of Drug-Induced Liver Injury

Jan Serroyen (J&J)

 

 Safety

Virtual Control Groups in Preclinical Drug Safety Assessment

Dingzhou Li (Pfizer)

Safety

Innovating Preclinical Statistics Education

Jacob Fiksel (Vertex)

Safety

Comparative Study of Experimental Designs

Bing Liu (Pfizer)

Safety

Analyzing Digital endpoints Using LASSO and Elastic Net Techniques

Kanaka Tatikola (J&J)

Safety

Sample Size Reduction in Preclinical Experiments: A Bayesian Sequential Decision-Making Framework

Jizhou Kang (UC Santa Cruz)

 

 Emerging Tools

Differential Projection Pursuit on Flow Cytometry Data to Identify and Profile Immune Cells Compromised by Exposure to HIV

Davit Sargsyan (J&J)

 

Emerging Tools

Evaluation of Quality Document Retrieval Tools Using Synthetic Examples

Zhoushanyue He (Roche)

Emerging Tools

SubVision: Deep Learning to Accelerate Biopharmaceutical Formulation Development

Yue-Ming Chen (Merck)

Emerging Tools

Illuminating the role of statistics in GenAI

Stephanie Young (J&J)

Emerging Tools

Application of Causal Machine Learning in Pharmaceutical Manufacturing

Ranran Dong (Genentech)

Emerging Tools

Modern Tools to Meet the Challenges of Preclinical Translation to the Clinic

Steven Novick (Takeda)

 


Poster Presentations

Area(s)

Title

Presenter

Safety

Statistical Approaches to Evaluate the Positive Control Drug using the hERG Assay

Yu-Ting Weng (FDA)

CMC

Application of Tree-based Machine Learning Techniques in cell-gene therapy experiments

Hong Tran (J&J)

CMC

Is your Excipient Robustness Study Telling the Full Story?

Lina Niu (Pfizer)

CMC

Comparison of Bland-Altman, Passing-Bablok Regression, the Tan’s Method and CCC in Method Agreement Analysis

Kang Liu (Pfizer)

CMC

Rethinking Scale Down Model Qualification: Some Statistical Evolutions

Chelsey Bennett (Sanofi)

CMC

Automated Data Import Toolkits for Non-clinical and CMC Statisticians to Maintain Data Quality

Edem Defor (Takeda)

CMC

A Comparison between Frequentist vs. Bayesian in Stability Data Analysis

Yang Xu (Merck)

CMC

Dealing with Non-Normality in Lot Uniformity Testing

Yanbing Zheng (AbbVie)

CMC

Semi-parametric Regression Techniques Applied to Biologics Development

Georgette Asherman (Merck)

Discovery

BioPred: an R package for biomarkers analysis in precision medicine

Zihuan Liu (AbbVie)

Discovery

Leveraging Knowledge Graphs to Accelerate Drug Discovery

Yue Yang (Takeda)

Discovery

An Information Criterion Approach for Assessing Agreement When Comparing Two Methods of Measurement

Yi Wang (Pfizer)

Discovery

Algorithms to Identify the Linear Dynamic Range of a Calibration Curve

Andrew McKeen (Pfizer)

Discovery

Synergy-Informed Design of Platform Trials for Combination Therapies: False Positive Control, Allocation Optimization, and Sample Size Determination

Miles Xi (AbbVie)

Discovery

Metabolomics and lipidomics analyses aid model classification of type 2 diabetes in non-human primates

Peining Tao (Merck)

Emerging

Is the Grass Greener on the Other Side? Generating PDF Reports using LaTeX vs. Typst

Jocelyn Sendecki (J&J)

Student

Identifying Long Intergenic Non-Coding RNAs Involved in Immune Regulation in COVID-19 Using Gene Ontology-Based Correlation Analysis

Vahe Nersisyan (Rutgers University)

Student

Differential Projection Pursuit: A machine learning method to find regions with maximal difference between distributions

Mahan Dastgiri (Rutgers University)

Student

Parallelism of Four-Parameter Logistic Bioassay Models: Equivalence Testing for Parameter Differences

Ji Li (University of Maryland, Baltimore County)