Please find below information on an upcoming webinar, sponsored by both the Mental Health Statistics Section and the Biometrics Section.
Title: Some Frequently Asked Questions about the Design and Analysis of Sequential, Multiple Assignment Randomized Trials
Presenter: Daniel Almirall, University of Michigan
Date and Time: Wednesday, November 20, 2019, 12:00 p.m. – 1:30 p.m. Eastern time
Sponsor: Mental Health Statistics Section
Registration Deadline: Monday, November 18, at 12:00 p.m. Eastern time
Description:Dynamic treatment regimens (also known as adaptive interventions) use a sequence of decision rules that guide whether, how, or when-and, importantly, based on which measures-to make critical decisions about intervention (e.g., treatment) in clinical, education or policy settings. This includes whether, how or when to alter the dosage (duration, frequency, or amount), type, or delivery of interventions to patients, students (or organizations). These interventions seek to address the individual and changing needs of students (or organizations) as they progress through an intervention. A SMART is a type of multi-stage, experimental design that was developed explicitly for constructing effective DTRs. While research on DTRs and SMART methods has grown exponentially in the past few years, substantive scientists and applied statistical workers still have many questions about the design of a SMART. This could lead to misconceptions or to limiting the novelty or significance (impact) of the proposed study design.
This non-technical webinar begins to fill this gap. Specifically, this webinar highlights some important principles of design and data analysis for SMARTs using a "Frequently Asked Questions" approach. Specifically, we pose a number of FAQs (which may come either from the perspective of a substantive scientist or applied statistical worker) and we work through possible responses to them. The FAQs presented in this webinar are the most common among a longer compilation of FAQs which have been collected based on over 10 years of experience designing these trial designs. We cover topics such as the distinction between a DTR and a SMART, control groups, the role of randomization, sample sizes, and embedded tailoring variables. We illustrate these ideas using a number of studies aiming to develop high-quality DTRs in mental health.
This webinar promises to be of interest to a broad array of statistical scientists and their collaborators, including medical or behavioral intervention scientists, methodologists and biostatisticians.
Registration Fees: Member of the Mental Health Statistics or Biometrics Section: $60
ASA Member: $90
Nonmember: $110
Each registration is allowed one connection to the webinar. Multiple persons are encouraged to view each registered connection (for example, by projecting the webinar in a conference room).
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Adam Ciarleglio
Assistant Professor
George Washington University
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