Hello,
The Boston Chapter of the ASA is excited to host a webinar with Professor Ying Yuan from MD Anderson Cancer Center.
Here is the detail about the event:
Topic: BOIN Suite: a Bayesian Design Platform to Innovate Phase I Oncology TrialsDate/Time: Wed, January 18, 2023, 7:30 PM – 8:30 PM EST
Location: Online
Cost: Free
Registration Link: https://www.eventbrite.com/e/boin-suite-a-bayesian-design-platform-to-innovate-phase-i-oncology-trials-tickets-482708442947. Click or tap if you trust this link." data-linkindex="7">www.eventbrite.com/e/...
Talk Abstract:
US Food and Drug Administration (FDA) recently granted the Bayesian optimal interval (BOIN) design the fit-for-purpose designation as a tool for drug development. This is the third design that received this prestigious designation over the last decade. In this talk, I will review the statistical principle of BOIN designs and how they provide an integrated platform to accommodate various types of phase I trials, including single-agent trials, drug-combination trials, trials with late-onset toxicity, and trials to find the optimal biological dose. Practical guidance and software, freely available at www.trialdesign.org, will be provided with real-world trial examples.
Speaker Biography:
Ying Yuan, PhD, is a Bettyann Asche Murray Distinguished Professor and Deputy Chair in the Department of Biostatistics at the University of Texas MD Anderson Cancer Center. Dr. Yuan has published over 100 statistical methodology papers on innovative Bayesian adaptive designs, including early phase trials, seamless trials, biomarker-guided trials, and basket and platform trials. The designs and software developed by Dr. Yuan's lab (www.trialdesign.org) have been widely used in medical research institutes and pharmaceutical companies. The BOIN design developed by Dr. Yuan's lab is the first oncology dose-finding design designated as a fit-for-purpose drug development tool by FDA. Dr. Yuan was elected as the American Statistical Association Fellow, and wrote book "Bayesian Designs for Phase I-II Clinical Trials" and "Model-Assisted Bayesian Designs for Dose Finding and Optimization" published by Chapman & Hall/CRC.
In this webinar, Dr. Yuan will give a review of the BOIN designs. The webinar will be moderated by Dr. Zhaoyang Teng, Biostatistics Director, Head of LCM (GMPA, HEOR and Market Access) Biostatistics for Oncology, Head of Biostatistics in APAC at Servier Pharmaceuticals.
Registration link: https://www.eventbrite.com/e/boin-suite-a-bayesian-design-platform-to-innovate-phase-i-oncology-trials-tickets-482708442947. Click or tap if you trust this link." data-linkindex="8">www.eventbrite.com/e/...
Look forward to seeing you at the webinar!
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Jianjun Hua
Boston Chapter of ASA
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