Division of Biostatistics Seminar

When:  Nov 12, 2012 from 13:30 to 14:30 (ET)
Associated with  Southern Florida Chapter

Wensong Wu from FIU

BAYES MULTIPLE DECISION FUNCTIONS IN CLASSIFICATION

We consider a two-class classification problem, where the goal is to predict the class membership of M units based on the values of high-dimensional predictor variables as well as both the values of the predictor variables and the class membership of other N independent units. We consider a Bayesian and decision-theoretic framework, and develop a general form of Bayes multiple decision function (BMDF) with respect to a class of cost-weighted loss functions. In particular, the loss function pairs such as the proportions of false positives and false negatives, and (1-sensitivity) and (1-specificity), are considered, and the cost weights are pre-specified. An efficient algorithm of finding the BMDF is provided based upon posterior expectations. The result is applicable to general classification models, but particular generalized linear regression models are investigated, where the predictor variables and the link functions are to be chosen from a finite class. The results will be illustrated via simulations and on a Lupus diagnose dataset.

Location

University of Miami
Clinical Research Building
Suite 989
Miami, FL 33136

Contact

Michele Gomez
305-243-6312
MGomez6@biostat.med.miami.edu