Please join us for an exciting day of networking and continuing education events in Kansas City. The Kansas-Western Missouri Chapter of ASA and the University of Kansas Medical Center Department of Biostatistics are co-sponsoring an American Statistical Association Council of Chapters Traveling Short Course, and the annual Fall Chapter Meeting will be held at its conclusion. Short course and keynote address will both be given by Dr. Andrea Troxel from the University of Pennsylvania School of Medicine.
ASA Traveling Short Course: Pragmatic Clinical Trials
Presenter: Andrea Troxel, Ph.D. (University of Pennsylvania)
Date: November 11, 2016, 1:00 pm to 5:00 pm
Location: University of Kansas, Edwards Campus (Regents Center 110)
12600 Quivira Rd., Overland Park, KS 66213
Registration Fee: $50 for ASA members, $25 for students, $75 for non-ASA members
Abstract: There is increasing interest in exploring the comparative effectiveness of therapies for a wide range of conditions. Pragmatic clinical trials offer promise. Features of pragmatic trials include simplicity of interventions or treatments, limited eligibility criteria for participants, streamlined approaches to consent, contact with participants occurring within existing processes, and outcome data obtained through administrative sources such as existing electronic health records, claims data, or registries. Pragmatic trials must still include randomization as a fundamental tool to allow valid comparison of interventions. The desired features of pragmatic trials give rise to a number of design and analytic challenges. This course will review the structure of pragmatic trials, describe some of the special design issues, and offer new approaches to handle them. Examples from actual trials in biomedical research will be provided.
Biographical Sketch: Dr. Andrea B. Troxel is Professor and Associate Director of Biostatistics at University of Pennsylvania Perelman School of Medicine, Director of the Abramson Cancer Center's Biostatistics Core, Director of Biostatistics at the Leonard Davis Institute Center for Health Incentives and Behavioral Economics at Penn, and Senior Scholar in the Center for Clinical Epidemiology and Biostatistics. In addition to her extensive experience in the design, conduct, and analysis of all phases of clinical studies, she has published on missing data, sensitivity analyses, and the development of statistical methodology for analysis of clinical trials. Recently she has focused on issues in pragmatic clinical trials, including methods of consent, non-standard randomization, rapid-cycle innovation, and multiple comparisons. She is the author of more than 175 articles in the literature of statistical methodology, cancer, behavioral research, and other areas of medicine. Dr. Troxel is an elected Fellow of the American Statistical Association; Associate Editor of Statistics in Medicine, a premier journal in biomedical statistics; and serves on Data Safety Monitoring Boards (DSMBs) for randomized trials in cancer, cardiac devices, smoking cessation, and behavioral therapies.